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Due to lack of memory protection under AmigaOS, a number of tools exists that use MMUs to offer partial protection for debugging purposes during development.

MorphOS has built-in CyberGuard. It guards non-allocated memory and writes to zero page. It can be configured to guard reads from zero page but it is not enabled by default because many Amiga software would fail.

MorphOS SDK includes Wipeout. It is Mungwall replacement originally written by Olaf Barthel and then ported to MorphOS.

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Barfly is a debugger / disassembler / assembler that supports M68k and PPC, and that can handle source level debugging assuming the executable contains debug information.